SOURCE-LINKED INTELLIGENCE

INTELLIGENT ENCAPSULATION AND SCREENING PLATFORM FOR PRECISION DELIVERY OF PROBIOTICS TO IMPROVE GUT HEALTH

CORDIS · observation · Publication date unknown

ntrolled release of probiotics, we will develop and test a novel gut-on-a-chip microfluidic device. To obtain more in-depth knowledge as well as prepare for high-throughput screenings, we incorporate machine learning for i) automated investigation of digestion kinetics under personalizable conditions and ii) automated in-line identification, evaluation, and adjustment of microcapsule synthesis. As a proof of concept, we will leverage our encapsulation and screening platforms to protect a sensitive next-generation strain and make our precision probiotics formulation available to patients via personalized treatment of a patient cohort under pharmacy legislation. iNSIGHT forms the basis for protection and delivery of sensitive probiotic ingredients, and thereby contributes to the prevention, alleviation, and/or treatment of myriad health conditions related to unhealthy gut microbiota. Microencapsulation, probiotics, targeted release, microfluidics, reinforced machine learning, in vitro digestion and fermentation, high-throughput, patient cohort

Read original source ↗ Open in workspace

recordType

award

status

SIGNED

region

EU

value

3194343.75

unit

EUR