SOURCE-LINKED INTELLIGENCE

Large-scale subcellular ensemble dynamics in the mouse brain revealed by adaptive optics two-photon mesoscopy

CORDIS · observation · Publication date unknown

ks of thin astrocytic structures encode behavioural information over multiple cortical regions during a decision- making task. Finally, I will apply analytical methods based on information theory and machine learning to extract emergent properties of distributed ensembles and their correlation with behaviour. In conclusion, I will combine expertise in optical engineering, neuroscience, and computation to reveal the functional dynamics of the fine cellular structures across multiple cortical areas. This project will allow extracting details about ensemble dynamics that have long remained inaccessible, contributing to elucidate the contribution of coordinated activity of cellular and subcellular structures to higher brain function and behaviour. adaptive optics, two-photon random access microscopy, calcium imaging, sub-cellular resolution, astrocytes, L5 neurons, somatosensory cortex, motor cortex, information theory, machine learning

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recordType

award

status

SIGNED

region

EU

value

172750.08

unit

EUR