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Benchmarking Clinical Decision Pathway Adherence in Large Language Models

arXiv · AI, language, vision and robotics · article · Aug 27, 2026 · UTC

Following clinical decision pathways (CDPs) defined by clinical practice guidelines is essential for safe and reliable medical decision-making. However, existing medical large language model (LLM) benchmarks mainly evaluate final-answer accuracy, providing limited evaluation of models' ability to adhere to guidelines. To address this gap, we introduce MEGA-CDP, a benchmark for evaluating whether medical LLMs can generate guideline-adherent CDPs using provided guidelines as references. MEGA-CDP is constructed from 2,274 English and Chinese clinical practice guidelines through a guideline-to-cas

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Evidence & attribution

First collected: 2026-09-21T08:51:59.673Z. This is not the publication date.