SOURCE-LINKED INTELLIGENCE
Deciphering cellular and viral determinants of lytic HSV-1 infection, latency and reactivation
ral genome; and (iii) decipher the cellular and viral determinants of HSV-1 latency and reactivation. Alongside, I will develop new computational approaches and integrative analysis tools, and employ artificial intelligence to exploit the wealth of information that is provided by the novel single cell RNA sequencing approaches, which I will pioneer (Heterogeneity-seq and Perturb-scSLAM-seq). Thereby, I will deliver new leads for novel therapeutic approaches targeting HSV-1 latency and reactivation. This will provide a paradigm for the study of other herpesviruses and their complex host-pathogen interactions. Herpes simplex virus 1, latency, reactivation, viral elements, pervasive transcription, systems biology, single cell RNA-seq
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- recordType
- award
- status
- SIGNED
- region
- EU
- value
- 1998008.75
- unit
- EUR
Evidence & attribution
European Commission, CORDIS Horizon Europe project dataset. Metadata adapted.
License: CORDIS reuse policy
First collected: 2026-09-20T00:21:03.701Z. This is not the publication date.