SOURCE-LINKED INTELLIGENCE

AI-AIDED TOOL FOR DAY ZERO SELECTION OF HIGH PERFORMING CELLS FOR BIOPHARMA CELL LINE DEVELOPMENT - SUMMARY WITH THE INCREASING NUMBER OF PROTEIN THERAPEUTIC CANDIDATES, IDENTIFYING AND ISOLATING SINGLE-CELL DERIVED COLO

USAspending · observation · Publication date unknown

AI-AIDED TOOL FOR DAY ZERO SELECTION OF HIGH PERFORMING CELLS FOR BIOPHARMA CELL LINE DEVELOPMENT - SUMMARY WITH THE INCREASING NUMBER OF PROTEIN THERAPEUTIC CANDIDATES, IDENTIFYING AND ISOLATING SINGLE-CELL DERIVED COLONIES IS A CRITICAL STEP THAT IS CONDUCTED ROUTINELY AND FREQUENTLY IN MONOCLONAL ANTIBODY DRUG DEVELOPMENT AND MANUFACTURE. SINGLE CELL TECHNOLOGIES IN CELL LINE DEVELOPMENT (CLD) HAS GONE THROUGH A FEW STAGES: FIRST TO PLACE SINGLE-CELLS IN WELLS BY LIMITING DILUTION, THEN TO USE FACS, AND MORE RECENTLY, TO PLACE HIGH PROLIFERATION RATE SINGLE-CELLS INTO WELLS OF A MICROTITER

Read original source ↗ Open in workspace

recordType

award

region

US

value

1764496

unit

USD