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Development of novel 3D vascularized cardiac models to investigate Coronary Microvascular Disease

CORDIS · observation · Publication date unknown

nt. This model will enable unprecedented study of ischemia, diabetes, and sex-hormone contributions to CMD using 3D in vitro tissues. Ultimately, a high-throughput version of our model, combined with machine learning, will predict the efficacy of therapeutic targets. Using an interdisciplinary approach, 3DVasCMD will impact our understanding of how microenvironmental and heritable risk-factors contribute to CMD. This model has the potential to study multiple facets of vascular disease and can be further developed into a preclinical tool, which will be a breakthrough for cardiovascular biology and medicine. Vascularized in vitro cardiac model, high-throughput drug screens

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recordType

award

status

SIGNED

region

EU

value

1496395

unit

EUR