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Toward Markerless Video-based Tremor Analysis: Objective Quantification of Pathological Tremor in Mouse Preclinical Models

arXiv · AI, language, vision and robotics · article · Sep 16, 2026 · UTC

Tremor is a movement disorder characterized by involuntary, rhythmic oscillations of body parts and is a hallmark of several neurological conditions, including Parkinson's disease and essential tremor. Elucidating its underlying mechanisms relies heavily on mouse models, which offer genetic manipulability and translational relevance to human neural circuitry. Accordingly, these models are indispensable for studying tremor pathophysiology. So far, electromyography and accelerometers have been used as methods to quantitatively observe tremors in mice. However, these methods have several drawback

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