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Packora: Systematic Design for Generative Molecular Crystal Structure Prediction

arXiv · AI, language, vision and robotics · article · Aug 27, 2026 · UTC

Molecular crystal structure prediction (CSP) is important in pharmaceuticals, agrochemicals, and organic electronics, where subtle differences in molecular conformation and packing can strongly affect material properties. We present Packora, a flow-based generative model for molecular CSP that jointly predicts atomic coordinates and the lattice from molecular graphs. Packora supports multi-component and organometallic crystals and can condition on any subset of molecular conformers, stereochemical labels, and space-group information within a single model. Inspired by the CCDC CSP blind test, w

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First collected: 2026-09-21T08:51:59.673Z. This is not the publication date.