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Observation-Anchored Selective Assimilation for Longitudinal Tumor-State Proxy Forecasting in Post-Treatment Glioma

arXiv · AI, language, vision and robotics · article · Sep 11, 2026 · UTC

Post-treatment MRI in patients with glioma provides serial observations for updating patient-specific tumor-state proxy estimates, but variable appearances and trajectories complicate forecasting. We formulate forecasting as an observation-aware digital-twin update in which an intermediate observation anchors the patient-specific state. Among 203 patients and 594 follow-up time points, a predefined no-new-treatment criterion retained 120 of 236 candidate triplets, split into 81/24/15 training/validation/test triplets at the patient level. Each time point was represented by a continuous voxel-w

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First collected: 2026-09-20T18:42:18.733Z. This is not the publication date.