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Multi-Pass, Multi-View Blended Learning for High-Fidelity Volumetric CT Synthesis from Chest X-Rays

arXiv · AI, language, vision and robotics · article · Sep 9, 2026 · UTC

Reconstructing volumetric Computed Tomography (CT) from a single 2D chest radiograph (CXR) is an ill-posed inverse problem, further complicated by the scarcity of paired CXR-CT training data. Prior approaches address this by training on Digitally Reconstructed Radiographs (DRRs), which are synthetic projections derived from CT volumes. However, the domain gap between DRRs and real CXRs limits generalization, often resulting in coarse or anatomically inconsistent reconstructions when applied to clinical images. To address this challenging problem, this study introduces a Multi-Pass Multi-View B

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