SOURCE-LINKED INTELLIGENCE
Bacteria Intrinsically Orchestrated with Designed Enzymes for sinerGistic Rate-Accelerated plastic Degradation Efficiency
The additional active sites able to degrade plastics will designed into the proteins employing advanced molecular simulation techniques such Protein Energy Landscape Exploration (PELE) together with machine learning methods. In this way, the proteins will not be from other microbial origin (heterologous), but their homologous proteins, to which an extra active-site capable of hydrolysing microplastics will be designed and genetically added, not altering the gene expression pattern of the microorganisms. These organisms will outperform the use of single enzymes because of the synergistic action of multiple evolved enzymes with one common goal: (micro)plastic degradation. Biochemistry, Molecular Dynamics, Chemical Engineering, Biological System Analysis modelling and simulation, bioinformatics, Artificial Intelligence, Machine Learning, Computer Aided Design
Read original source ↗ Open in workspace
- recordType
- award
- status
- SIGNED
- region
- EU
- value
- 226441.2
- unit
- EUR
Evidence & attribution
European Commission, CORDIS Horizon Europe project dataset. Metadata adapted.
License: CORDIS reuse policy
First collected: 2026-09-20T01:21:06.728Z. This is not the publication date.