SOURCE-LINKED INTELLIGENCE

Smart bioreactor-based platform for the multi-phYsical stimulatioN of Engineered osteochondRal tissues towards functional reGeneratIon and advanced diseasE modelS

CORDIS · observation · Publication date unknown

eactor-based platform able to culture OC constructs under physiologically and clinically relevant multi-physical stimulations in a controlled and adaptive manner. Cutting-edge in silico modelling and machine learning (ML) tools will be employed for the operational parameters optimization and for the smart automated control of the bioreactor platform, respectively. The SYNERGIES platform will enhance the knowledge of OC tissue mechanobiology beyond the state-of-the-art and guide the improvement of protocols for the production of functional OC substitutes, which will be suitable in vitro models for OC disease research and drug screening, paving the way for new effective therapies. The proposed Fellowship will enable a highly interdisciplinary collaboration between myself, a talented post-doc with a strong track record on biomaterial scaffolds for OCTE, and the supervisors, leading experts on bioreactor engineering and in silico modelling/ML tools. The excellent working conditions at Politecnico di Torino and 7HC will promote my professional development, offering me new scientific expe

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recordType

award

status

TERMINATED

region

EU

value

188590.08

unit

EUR