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LUCERO BIO: Smart Optofluidic Isolation of Spheroids for Early-Stage Drug Discovery

CORDIS · observation · Publication date unknown

-derived 3D cell cultures while being scalable for high-throughput drug screening. Lucero fills this need by providing a novel cell-handling platform that combines microfluidics, optical tweezers and artificial intelligence. During our ERC PoC project, we developed an integrated benchtop device for in-vitro handling of single 3D cell cultures, in particular mini spheroids. Lucero will build on this achievement by expanding our prototype’s functionalities and adapting its design to automatically detect spheroid viability and fully automate their isolation, to match the drug screening workflow. By thoroughly testing the prototype’s performance and compatibility with our large European pharmaceutical partner on-site, we will mature our prototype to technological readiness level (TRL) 6. Based on their feedback we will increase our commercial readiness level (CRL) 6 and will be ready for the next acceleration phase. The intended result of this proposal is to introduce Lucero’s 3D cell-handling platform as an enabling tool for pharmaceutical companies to develop more effective “near-pati

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recordType

award

status

SIGNED

region

EU

value

1298712

unit

EUR