SOURCE-LINKED INTELLIGENCE

Revolutionary high-resolution human 3D brain organoid platform integrating AI-based analytics

CORDIS · observation · Publication date unknown

ray (MEA) technology for non-invasive high-resolution electrophysiological recordings and 3) a novel approach to analyse and interpret the large quantities of functional data using tailored automated machine learning (ML)-based algorithms. With this breakthrough approach we overcome significant hurdles that made it thus far impossible to create a truly representative and functional model of the CNS for personalized medicine, drug screening and neurotoxicity testing. The revolutionary 3D-BrAIn high-precision CNS platform will allow robust and accurate modelling of the CNS for a broad range of neuropsychiatric diseases. Ultimately, the 3D-BrAIn technology will be translatable to multiple other organ systems (cardiomyocytes, pancreatic islets, retina), to non-invasively obtain longitudinal 3D high-resolution electrophysiological recordings and effectively interpret them. In this project a prototype of the 3D-BrAIn platform will be developed by growing functional 3D organoids that faithfully resemble the human cortex on 3D MEA micropillar electrodes, enabling continuous functional moni

Read original source ↗ Open in workspace

recordType

award

status

SIGNED

region

EU

value

1998347

unit

EUR