SOURCE-LINKED INTELLIGENCE

Systematic Triangulation of Pathobiont-Host-Interactions

CORDIS · observation · Publication date unknown

ave developed an antibody coating based approach, to identify and culture pathobionts. Now, we want to overhaul our approach to develop a high throughput-pathobiont identification technology. Through machine learning, we then aim to find pathobiont-host genetic risk matches that drive disease and validate these matches in vivo. Lastly, we plan to demonstrate the potential of our new technology and gained knowledge. Through leveraging the gained knowledge, we aim to identify pathobiont-host risk matches in publicly available databases. This will unmask individuals at risk for the development of IBD, CRC and potentially other disorders. This may pave the way for future microbiome-based precision medicine approaches. Microbiome, host genetic risk, host-pathobiont interaction, immune system, chronic disorders, bioinformatics

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recordType

award

status

SIGNED

region

EU

value

1993688

unit

EUR