SOURCE-LINKED INTELLIGENCE

ORIGIN - Optimized Routing and Industrial Generation of Ingredients from Nature​

CORDIS · observation · Publication date unknown

pecting, leveraging the world’s largest proprietary, Nagoya-compliant metagenomic database (>10 billion sequences, >1M new species); (ii) AI-driven retrosynthesis and host-aware pathway design; (iii) generative AI-guided enzyme engineering; (iv) multi-host rapid prototyping across E. coli, S. cerevisiae, Y. lipolytica, and A. niger. These are unified by the (v) ORIGIN Co-pilot, a central LLM-based agentic AI serving as an “automated scientist” that integrates data streams across the whole project into a closed-loop Design–Build–Test–Learn cycle. By project completion, ORIGIN will deliver AI-optimized pathway blueprints for 50 molecules, 10 validated microbial strains, and 3molecules demonstrated at pilot scale (30L to 100L), achieving >10 g/L titers and >95% purity. This will reduce time-to-market from 5–10 years to 2–3 years, cut land use by >90% and GHG emissions by 30–50%, and ensure EU leadership in climate-neutral, biodiversity-friendly bioproduction. Biodiversity preservation, Circular bioeconomy, Strategic autonomy, Climate-neutral biomanufacturing, Sustainable value chains, S

Read original source ↗ Open in workspace

recordType

award

status

SIGNED

region

EU

value

5498237

unit

EUR