SOURCE-LINKED INTELLIGENCE

Cell-mediated sculptable living platforms as highly efficient hybrid units to bioengineer human microtissues

CORDIS · observation · Publication date unknown

thin the films to create a living platform able to guide stem cells toward osteogenic differentiation. Cell behaviour will be correlated with local structural data from the pockets and analysed using deep learning to identify favourable geometrical and structural descriptors that could help to engineer bioactive improbable synthetic niches. Computer modelling will identify optimal conditions for producing high-quality microtissues, with applications in regenerative medicine and pre-clinical disease modelling. These insights will also assist in scaling tissue engineering through assembly-based biofabrication techniques to generate hierarchical living constructs with unprecedent biological features. Bioengineering; Tissue Engineering; Soft-matter Computer Modelling; Genetic Engineering

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recordType

award

status

SIGNED

region

EU

value

9999343

unit

EUR