SOURCE-LINKED INTELLIGENCE

AnBioLED Ancestral Fluorescent Proteins as Biophosphors for Light-Emitting Diodes

CORDIS · observation · Publication date unknown

lly evolved to function as color converters in electronic devices. Since it is not possible to artificially evolve proteins under LED operation conditions (stress), AnBioLED proposes to merge through machine learning evolutionary information (Ancestral Sequence Reconstruction) and computational protein design to identify key mutations in order to improve FPs photo and thermal stability. More importantly, AnBioLED will use experimental results under device operation conditions to reinforce the protein design strategy. The new ancestral FPs will merge the excellent photoluminescence properties of existing FPs with the robustness of their ancestors. AnBioLED novel approach will allow for the first time to optimize existing FPs for LEDs applications. Bio-Hybrid White Light-Emitting Diodes, Protein Engineering, Fluorescent Proteins, Biomaterials

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recordType

award

status

SIGNED

region

EU

value

173847.36

unit

EUR