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Advancing Breast cancer Individualised Generative AI for Longitudinal Outcomes

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Advancing Breast cancer Individualised Generative AI for Longitudinal Outcomes ABIGAIL4D pioneers a new approach to personalised oncology by developing and validating a 4D Generative AI system prototype that can learn disease evolution over time and support safer, more informed treatment decisions in early breast cancer. Today, decision support tools rely on static or single-modality data and cannot estimate how an individual patient would respond to alternative therapies. This limits clinical ability to compare options and optimise outcomes. ABIGAIL4D combines multimodal longitudinal data, including imaging, pathology, genomics, and clinical variables, into a temporal model that reconstructs and forecasts tumour response, survival and toxicity. The system introduces counterfactual analysis to estimate patient-specific benefit and risk for different treatment strategies, such as escalation and de-escalation of chemotherapy or

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recordType

award

status

SIGNED

region

EU

value

4819131.31

unit

EUR