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Hyperpolarized Surface-enhanced Liquid-State Spectroscopy

CORDIS · observation · Publication date unknown

ilding Autonomous Interface Devices (AID): versatile and adaptable instrumentation to seamlessly update any NMR spectrometer with dDNP capabilities. 2) Maximized Substrate Scope will be achieved with artificial intelligence-driven Liquid-state Surface-ENhanced Spectroscopy (LiSENS): a resolution-enhanced method for dDNP-powered studies that uses simply water as a transporter of signal intensity. Thus, the requirement for the 10,000-fold signal boost by dDNP is narrowed down to mere solubility. 3) Confirmation of the versatility and prowess of AID and LiSENS will be achieved by providing super-resolution data at maximized sensitivity for an extensive set of cutting-edge applications in biomimetic materials, structural biology, and chemistry. HypSurf has the potential to set a new standard for NMR by boosting both resolution and sensitivity by orders of magnitude beyond the current state-of-the-art. With extensive expertise in dDNP instrumentation, NMR methods, and biochemistry, the PI is uniquely positioned to lead this ambitious initiative. NMR Spectroscopy, Hyperpolarization, Artif

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recordType

award

status

SIGNED

region

EU

value

1998020

unit

EUR